"An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)" (Source: MeSH)
Database of high quality systematic reviews in medicine. Even though the full text of articles is not always available, the results and conclusions in the abstracts can be very useful. This database also contains an extensive set of randomized controlled trials. For more information on Cochrane reviews and the method used to conduct them, see the handbook below.
"The CPG Infobase is a database of evidence-based Canadian clinical practice guidelines (CPGs). Maintained by Joule™, a CMA company, it includes approximately 1,200 CPGs developed or endorsed by authoritative medical or health organizations in Canada."